On Outlook, a profile includes your accounts, data files, settings and preferences. If you’re having problems syncing, you’re seeing errors, or you no longer need the profile, you can delete it from your computer.
When you delete an Outlook profile, you’ll be deleting all the downloaded emails. However, any Personal Folders Files (pst) associated with the profile will stay on your device, and it can later be accessed from a new profile.
How to delete profile in Outlook
Use these steps to delete an Outlook app profile on Office 365, Office 2019, Office 2016, and older versions:
Open Control Panel.
Click on User Accounts.
Click on Mail (Microsoft Outlook 2016).
Under the “Profiles” section, click the Show Profiles button.
Select the profile.
Click the Remove button.
Click the Yes button to confirm deletion.
Click the OK button.
Once you complete the steps, the profile with its accounts along with offline cache will be deleted from your device. The next time you open the desktop version of Outlook, you’ll need to set up your accounts again, which should help you to start fresh or fix issues with your accounts or app.
If you have multiple profiles, you may need to repeat the steps to delete them.